Dr. Nafiu Aminu

Area of specialization:	• Nano Pharmaceutics • Drug Delivery • Drug formulations and product development
Email:	nafiu.aminu@udusok.edu.ng
Phone:

List of Selected Publications

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1) Aminu, N.,Ilyasu, S., Al-Kassim Hassan, M., Kurfi, F. S., Jatau, A. I., Chan, S.-Y., & Alfred-Ugbenbo, D. (2023). Applications of nanofibers drug delivery system in cancer therapy. Journal of Drug Delivery Science and Technology, 90, 105128. https://doi.org/10.1016/j.jddst.2023.105128

2) Aminu, N., Khalid, G. M., Ilyasu, S., Yahaya, Z. S., Shuaibu, F., Nuhu, T., Chan, S.Y., Umar, N. M., Mumuni, M. A. (2023). Pharmaceutical sterile formulations. In: A. K. Nayak& K. K. Sen (Eds.), Dosage Forms, Formulation Developments, and Regulations (pp. 577–611). London, United Kingdom: Elsevier. https://doi.org/10.1016/B978-0-323-91817-6.00004-8

3) Aminu, N., &Audu, M. M. (2023). Polycaprolactone-based nanoparticles for advanced therapeutic applications. In: M. S. Hasnain, A. K. Nayak, & T. M. Aminabhavi (Eds.), Polymeric Nanosystems (1st ed., pp. 37–84). London, United Kingdom: Elsevier. https://doi.org/10.1016/B978-0-323-85656-0.00003-6 4) Abubakar, B., Giaze, R. T., Nasir, I., &Aminu, N. (2023). Toxicity assessment of methanol extract of Combretummicranthum in Drosophila melanogaster. Caliphate Journal of Science and Technology, 2, 204–211. https://doi.org/10.4314/cajost.v5i2.15

5) Abubakar, B., Yahaya, Z., Alhaji, S. A., Giaze, R. T., &Aminu, N. (2023). Phytochemical Screening and Toxicity Study of Methanol Stem Bark Extract of Prosopisafricana (African Mesquite) In Albino Wistar Rat. Dutse Journal of Pure and Applied Sciences, 9(2b), 117–126. https://doi.org/10.4314/dujopas.v9i2b.13

6) Hassan, L. G., Aminu, N., Mustapha, Y. M., Adiya, Z. I. S. G., Agwaba, E. C., &Salihu, M. (2023). Acetylation and Physicochemical Properties of Ampelocissusafricana (Wild Cassava Tuber) Starch for Enhanced Drug Delivery. Tropical Journal of Natural Product Research, 7(7), 3292–3296. https://doi.org/10.26538/tjnpr/v7i7.4

7) Malami, D. I., Aminu, N.,Jatau, A. I., Hassan, M. A.-K., Ilyasu, S., & Daniel, A. (2022). Empirical Quality Evaluation of Common Brands of Ceftriaxone Sodium Injection Marketed in the Northern Region of Nigeria. Malaysian Journal of Pharmaceutical Sciences, 20(2), 1–14. https://doi.org/10.21315/mjps2022.20.2.1

8) Aminu, N. (2022). Nanovesicles for drug codelivery. In: A. K. Nayak, M. S. Hasnain, T. M. Aminabhavi, & V. P. Torchilin (Eds.), Applications of Nanovesicular Drug Delivery (pp. 21–37). London: Elsevier. https://doi.org/10.1016/B978-0-323-91865-7.00023-7

9) Borodo, S. B., Jatau, A. I., Mohammed, M., Aminu, N., Shitu, Z., &Sha’aban, A. (2022). The burden of polypharmacy and potentially inappropriate medication in Nigeria: a clarion call for deprescribing practice. Bulletin of the National Research Centre, 46(1), 178. https://doi.org/10.1186/s42269-022-00864-3

10) Khan, N. H., Abdulbaqi, I. M., Darwis, Y., Aminu, N.,& Chan, S.Y. (2022). A stability-indicating HPLC-UV method for the quantification of anthocyanin in Roselle (Hibiscus Sabdariffa L.) spray-dried extract, oral powder, and lozenges. Heliyon, 8(3), e09177. https://doi.org/10.1016/j.heliyon.2022.e09177

11) Mumuni, M. A., Amarachi, C. S., Victor, A. C., Romanus, O. C., Ogbonna, J., Aminu, N., James, O. Y., Muhammed, A., Franklin, K., Díaz, D. D. (2022). A novel formulation design based on hetero-templated solid lipid microparticles to improve the solubility of anti-inflammatory piroxicam for oral administration. New Journal of Chemistry, 46(8), 3961–3965. https://doi.org/10.1039/D1NJ05281K

12) Mustapha, Y. M., Hassan, L. G., Adiya, I. S. G. Z., Aminu, N., &Agwamba, E. C. (2022). Characterization of Crude Starch Extract of Wild Cassava Tuber (Ampelocissusafricana). Bayero Journal of Pure and Applied Sciences, 13(1), 260–266. https://doi.org/10.4314/bajopas.v13i1.41S

13) Aminu, N., Yam, M.F., Chan, S.Y., Bello, I., Umar, N. M., Nuhu, T., &Toh, S.M. (2021). The evaluation of healing effect of triclosan and flurbiprofen-loaded nanogels in experimental periodontitis in rats by morphometric analysis. The Saudi Dental Journal, 33(7), 554–559. https://doi.org/10.1016/j.sdentj.2020.08.008

14) Aminu, N., Chan, S., Mumuni, M. A., Umar, N. M., Tanko, N., Zauro, S. A., Aminu, A., Toh, S. (2021). Physicochemical compatibility studies of triclosan and flurbiprofen with excipients of pharmaceutical formulation using binary, ternary, and multi-combination approach. Future Journal of Pharmaceutical Sciences, 7(1), 148. https://doi.org/10.1186/s43094-021-00302-7

15) Aminu, N.,& Zafar, M. S. (2021). Roles of nanomedicines in dental therapeutics. In: A. K. Shukla (Ed.), Nanotechnology for Dentistry Applications (pp. 4-1 – 4-32). Bristol, UK: IOP Publishing. https://doi.org/10.1088/978-0-7503-3671-0ch4

16) Oyinaka, B., Umar, N., Aminu, N., Akinleye, C., &Nuhu, T. (2021). Knowledge and attitude of primary healthcare workers towards rational prescription of Artemisinin-based combination therapy in the treatment of uncomplicated malaria in Ondo State, southwestern Nigeria. Journal of Pre-Clinical and Clinical Research, 15(1), 5–14. https://doi.org/10.26444/jpccr/131762 17) Teoh, X. Y., Goh, C. F., Aminu, N., & Chan, S. Y. (2021). Quantification of atovaquone from amorphous solid dispersion formulation using HPLC: An in vitro and ex vivo investigation. Journal of Pharmaceutical and Biomedical Analysis, 192, 113631. https://doi.org/10.1016/j.jpba.2020.113631

18) Mumuni, M. A., Ernest, O. C., Ebele, O., Kenechukwu, F. C., Salome, C. A., Chinekwu, N. S., Aminu, N., Ben, A. (2020). Development and Characterization of Mucinated Chitosan Microcomposite for Oral Insulin Delivery. Tropical Journal of Natural Product Research, 4(11), 1000–1006. https://doi.org/10.26538/tjnpr/v4i11.27

19) Aminu, N., Bello, I., Umar, N. M., Tanko, N., Aminu, A., &Audu, M. M. (2020). The influence of nanoparticulate drug delivery systems in drug therapy. Journal of Drug Delivery Science and Technology, 60, 101961. https://doi.org/10.1016/j.jddst.2020.101961

20) Aminu, N., Ado, W. I., Musa, H., Mumuni, M. A., &Gwarzo, M. S. (2020). Assessment of Physicochemical Properties of Glibenclamide Tablets Marketed in Zaria, Kaduna State, Nigeria. African Journal of Pharmaceutical Research & Development, 12(2), 242–247.

21) Umar, N. M., Parumasivam, T., Aminu, N., &Toh, S. M. (2020). Phytochemical and pharmacological properties of Curcuma aromaticaSalisb (wild turmeric). Journal of Applied Pharmaceutical Science, 10(10), 180–194. https://doi.org/10.7324/JAPS.2020.1010018

22) Mumuni, M. A., Calister, U. E., Aminu, N., Franklin, K. C., Musiliu, A. O., Usman, M., Abdulmumuni, B., James, O. Y., Ofokansi, K. C., Anthony, A. A., Ibezim, E. C. & David, D. (2020). Mucin-Grafted Polyethylene Glycol Microparticles Enable Oral Insulin Delivery for Improving Diabetic Treatment. Applied Sciences, 10(2649), 1–14. https://doi.org/10.3390/app10082649

23) Momoh, M. A., Kenechukwu, F. C., Nwagwu, C. S., Uzor, P., Obieze, V., Aminu, N., Oyeniyi, J., Ofomatah, A. C., Isah, A, &Salihu, S. M. (2020). Formulation and in vitro characterization of ibuprofen-loaded solid dispersions. African Journal of Pharmaceutical Research and Development, 12(1), 56–69.

24) Momoh, M. A., Ugwu, C. E., Kenechukwu, F. C., Adedokun, M., Agboke, A., Amadi, C. B., Eze, H., Aminu, N., Oyeniyi, J., &Attama, A. A. (2020). Development of amorphous lipid-polymer hybrid for improved solubility of a poorly-water soluble-drug: Glibenclamide as a model drug. African Journal of Pharmaceutical Research and Development, 12(1), 97–108.

25) Bello, I., Usman, N. S., Dewa, A., Abubakar, K., Aminu, N., Asmawi, M. Z., & Mahmud, R. (2020). Blood pressure lowering effect and vascular activity of Phyllanthusniruri extract: The role of NO/cGMP signaling pathway and β-adrenoceptor mediated relaxation of isolated aortic rings. Journal of Ethnopharmacology, 250, 112461. https://doi.org/10.1016/j.jep.2019.112461

26) Aminu, N., Chan, S. Y., Yam, M. F., &Toh, S. M. (2019). A dual-action chitosan-based nanogel system of triclosan and flurbiprofen for localised treatment of periodontitis. International Journal of Pharmaceutics, 570, 118659. https://doi.org/10.1016/j.ijpharm.2019.118659

27) Aminu, N., Chan, S.Y., Khan, N. H., Farhan, A. B., Umar, M. N., &Toh, S.M. (2019). A simple stability-indicating HPLC method for simultaneous analysis of paracetamol and caffeine and its application to determinations in fixed-dose combination tablet dosage form. ActaChromatographica, 31(2), 85–91. https://doi.org/10.1556/1326.2018.00354

28) Aminu, N., Chan, S. Y., &Toh, S. M. (2018). Formulation design and optimization of triclosan loaded nanoparticles for enhanced drug delivery across gingival sulcus by Resolution IV modeling of Design-Expert®. Journal of Biomedical and Clinical Sciences, 3(1), 83–90.

29) Umar, M. N., Mustapha, B., Tanko, N., &Aminu, N. (2018). Antibiotic Susceptibility Testing for Escherichia Coli Causing Urinary Tract Infections in Sokoto Metropolis. Asian Journal of Pharmaceutical and Clinical Research, 11(6), 373–376. https://doi.org/10.22159/ajpcr.2018.v11i6.21086

30) Aminu, N., Chan, S.Y., &Toh, S.M. (2018). Development and Validation of a Stability-indicating HPLC-UV Method for the Simultaneous Determination of Flurbiprofen and Triclosan in Dental Nanogel Formulations. Journal of Physical Science, 29(Suppl. 1), 1–7. https://doi.org/10.21315/jps2018.29.s1.1

31) Aminu, N., Chan, S.Y., Khan, N. H., &Toh, S.M. (2018). Concurrent determination of triclosan and flurbiprofen by high-performance liquid chromatography in simulated saliva and its application in dental nanogel formulation. ActaChromatographica, 30(4), 219–224. https://doi.org/10.1556/1326.2017.00286

32) Aminu, N., Sha’aban, A., Abubakar, A., &Gwarzo, M. S. (2017). Unveiling the peril of substandard and falsified medicines to public health and safety in Africa: Need for all-out war to end the menace. The Journal of Medicine Access, 1(1), 145–154. https://doi.org/10.5301/maapoc.0000023

33) Aminu, N., &Gwarzo, M. S. (2017). The imminent threats of counterfeit drugs to quality health care delivery in africa: Updates on consequences and way forward. Asian Journal of Pharmaceutical and Clinical Research, 10(7), 63–67. https://doi.org/10.22159/ajpcr.2017.v10i7.18384

34) Aminu, N., Chan, S., &Toh, S. (2017). Roles of Nanotechnological Approaches in Periodontal Disease Therapy. Journal of Applied Pharmaceutical Science, 7(07), 234–242. https://doi.org/10.7324/JAPS.2017.70735

35) Aminu, N., &Toh, S. (2017). Applicability of Nanoparticles-Hydrogel Composite in Treating Periodontal Diseases and Beyond. Asian Journal of Pharmaceutical and Clinical Research, 10(2), 65–70. https://doi.org/10.22159/ajpcr.2017.v10i2.15709

36) Pramod, K., Aminu, N., & Ali, J. (2014). Targeted Drug Delivery Systems for the Treatment of Periodontal Infections. In B. Singh, O. P. Katare, & J. N. Govil (Eds.), Biotechnology Volume 8: Novel Drug Delivery (pp. 97–128). U.S.A.: Studium Press LLC. http://www.studiumpress.in/biotechnology-volume-8-novel-drug-delivery.html

37) Aminu, N., Baboota, S., Pramod, K., Singh, M., Dang, S., Ansari, S. H., Sahni, J. K., & Ali, J. (2013). Development and evaluation of triclosan loaded poly-ε-caprolactone nanoparticulate system for the treatment of periodontal infections. Journal of Nanoparticle Research, 15(11), 2075. https://doi.org/10.1007/s11051-013-2075-6

List of conferences/workshops/seminar Papers

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1) Aminu, N, Alfred-Ugbenbo, D, Moradeke, O and MumuniM.A (2022). Development and assessment of antibacterial effect of Azadirachtaindica-loaded nanogel system for wound healing. A paper presented (ORAL) during the 20th Nigeria Association of Pharmacists in Academia (NAPA) National Conference, held on 15th – 19th August, 2022 at Obafemi Awolowo University, Ile-Ife, Nigeria.

2) Mustapha Y.M., LawalG.H., ZainabI.S.G., Aminu N., E.C. Agwamba (2022). Characterization of crude starch extract of wild cassava tuber (Ampelocissus Africana). A paper presented (ORAL) during the 2022 International Science Conference held 18th – 21st January 2022 at Bayero University Kano, Nigeria.

3) Aminu N., Sidi, H.A and Faruk, U.Z (2021). Dermal-gel formulation of an isolate of leaves extract of Guierasenegalensis for topical application: preparation, antibacterial study, and characterization. A paper presented (ORAL) during 19th Nigeria Association of Pharmacists in Academia (NAPA) Conference, held on 16th – 20th August, 2021 at University of Nigeria, Nsukka.

4) Aminu N., Kabir, A.M., Musa, H. and Momoh, M.A. (2020). Quality Control Assessment of Brands of Ciprofloxacin Caplets Marketed in Kaduna, Nigeria. A paper presented (ORAL) during 18th Nigeria Association of Pharmacists in Academia (NAPA) Conference, held on 24th – 26th August, 2020 at University of Nigeria, Nsukka.

5) Nafiu Aminu (2019). A Novel Chitosan-Based Nanogel System Co-Loaded with Triclosan and Flurbiprofen for Localized Treatment of Periodontitis. A paper presented (ORAL) during 2nd International Postgraduate Symposium in Biotechnology 2019 (IPSB 2019), held on 24-25 September 2019 at Institute of Bioproduct Development, UniversitiTeknologi Malaysia, Malaysia.

6) Nafiu Aminu (2019). Development and evaluation of stimuli responsive nanogel system loaded with triclosan and flurbiprofen for treatment of periodontitis. A paper presented (ORAL) during UniversitiSains Malaysia 3 Minutes Thesis Competetion held on 9th April 2019 at Dewanpembangunansiswa 2, komplekscahaya, main campus, UniversitiSains Malaysia, Penang, Malaysia.

7) Nafiu Aminu, Siok-Yee Chan, Ahmed Bassam Farhan, Seok-Ming Toh (2019). Current Technologies used in the Characterization of Nanoparticulate Systems. A paper presented (POSTER) during 3rd Asian Conference on Science, Technology and Medicine, held on 12-14 February, 2019 at Carlton Palace Hotel, Deira, Dubai, United Arab Emirate

8) Nafiu Aminu, Siok-Yee Chan, Mun-Fei Yam, Seok-Ming Toh (2019). A Novel Nanotechnology-Based Strategy for Effective Treatment of Periodontitis. A paper presented (ORAL) during 3rd Asian Conference on Science, Technology and Medicine, held on 12-14 February, 2019 at Carlton Palace Hotel, Deira, Dubai, United Arab Emirate

9) Nafiu Aminu, Siok-Yee Chan, Mun-Fei Yam, Nura Muhammad Umar, Seok-Ming Toh (2019). Anti-plaque and Anti-inflammatory Effects of Triclosan and Flurbiprofen-loaded Nanogels on Ligature Induced Periodontitis in Rats. A paper presented (POSTER) during Drug Delivery Seminar Series 1-2019 held on 14 January 2019 at School of Pharmaceutical Sciences, UniversitiSains Malaysia, Penang, Malaysia.

10) Nafiu Aminu and Seok-Ming Toh (2019). Targeted and stimuli responsive nanogel system for effective intra-pocket drugs delivery for the treatment of dental disorder. A paper presented (ORAL) during Drug Delivery Seminar Series 1-2019 held on 14 January 2019 at School of Pharmaceutical Sciences, UniversitiSains Malaysia, Penang, Malaysia.

11) Nura Muhammad Umar, Nafiu Aminu and TohSeok Ming (2019). Advances in Chronic Wound Healing; Challenges and Way forward. A paper presented (POSTER) during Drug Delivery Seminar Series 1-2019 held on 14 January 2019 at School of Pharmaceutical Sciences, UniversitiSains Malaysia, Penang, Malaysia.

12) Nafiu Aminu (2018). Contribution pharmacists can offer in improving community healthcare: Experience from Nigerian practice. A paper presented (POSTER) during the national conference of the Pharmaceutical Society of Australia 2018 (PSA18), 27th – 29th July 2018, held at Hyatt Regency Sydney, Australia.

13) Nafiu Aminu (2018). Development and evaluation of multi-drug loaded nanogels delivery system for the treatment of periodontal disease. A paper presented (POSTER) during the national conference of the Pharmaceutical Society of Australia 2018 (PSA18), 27th – 29th July 2018, held at Hyatt Regency Sydney, Australia.

14) Nafiu Aminu, Siok Yee Chan, Seok Ming Toh (2018). Systematic optimization of triclosan loaded nanoparticles formulation by Design Expert® for improved local delivery in the treatment of periodontal infection. A paper presented (POSTER) during the 3rd AMDI International Biohealth Sciences Conference (IBSC) 2018, 19th – 20th January 2018, held at Riverside Majestic Hotel Kuching, Sarawak, Malaysia.

15) Nafiu Aminu, Siok Yee Chan, MunFei Yam, Seok Ming Toh (2018). Development, characterization and in vivo evaluation of triclosan loaded nanoparticles against periodontal infection. A paper presented (ORAL) during the 3rd AMDI International Biohealth Sciences Conference (IBSC) 2018, 19th – 20th January 2018, held at Riverside Majestic Hotel Kuching, Sarawak, Malaysia.

16) Nafiu Aminu, MunFei Yam, Siok Yee Chan, Idris Bello, Seok Ming Toh (2018). Simplified ligature-induced periodontitis model in rats for better diagnosis. A paper presented (ORAL) during the 3rd AMDI International Biohealth Sciences Conference (IBSC) 2018, 19th – 20th January 2018, held at Riverside Majestic Hotel Kuching, Sarawak, Malaysia.

17) Nafiu Aminu, Chan Siok Yee and TohSeok Ming (2017). Compatibility studies of triclosan and flurbiprofen with formulation excipients: a systematic drug-drug and drugs-excipients compatibility screening. A paper presented (ORAL) during the 13th MPS-USM Pharmacy Scientific Conference, 3-5 November 2017, held at Bayview Beach Resort Hotel, Penang, Malaysia.

18) Nafiu Aminu, Chan Siok Yee and TohSeok Ming (2017). Validated Stability-indicating HPLC-UV Method for the Simultaneous Determination of Flurbiprofen and Triclosan in Dental Nanogel Formulation. A paper presented (ORAL) during the International Conference for Young Chemists (ICYC) 2017, held at St. Giles The Wembley Hotel, Georgetown, Penang, Malaysia on 16 – 18th August 2017.

19) Nafiu Aminu and Javed Ali (2016). Recent Nanotechnological Approaches for the Effective Treatment of Periodontitis. A paper presented (POSTER) during International Conference on Pharmacy Education and Practice, 29 – 31 January 2016, held at Bayview Beach Resort Hotel, Penang, Malaysia.

20) Nafiu Aminu and TohSeok Ming (2016). Nanoparticles-hydrogel composite as a novel intra-pocket drug delivery system for the treatment of periodontitis. A paper presented (POSTER) 2nd AMDI International Biohealth Sciences Conference, 27th – 28th January 2016, held at Sains@USM, Penang, Malaysia. 21) Nafiu Aminu and Aliyu Muhammad (2015). Counterfeit and fake medicines posed eminent threat to delivery of quality health care to our society. A paper presented (ORAL) at 16th Islamic Medical Association of Nigeria’s National Scientific Conference, 30th July – 2nd August, 2015 held at Gusau, Nigeria.

22) Nafiu Aminu and Sushil Tiwari (2009). The impact of the current global economic meltdown on the pharmaceutical industries. A presented (POSTER) during AICTE Sponsored National Seminar, with the theme: Emerging Trends in Pharmaceutical Sciences held on 21st - 22nd March, 2009 at Faculty of Pharmacy, JamiaHamdard (Hamdard University), New Delhi, India.

23) Nafiu Aminu (2009). Liposomes: A novel drug delivery with broad marketing scope. A paper presented (ORAL) during proceedings of National Marketing Seminar “Building Brands – The Indian Way” held on 21st November, 2009, at JamiaHamdard (Hamdard University), New Delhi, India.

24) Nafiu Aminu (2008). Scope of Herbal Drugs in Drug Delivery System. A paper presented (ORAL) during scientific session of the 60th Indian Pharmaceutical Conference, 12th – 14th December, 2008 held at New Delhi, India.

Academic Metrics (ORCID, LinkedIn, Google scholar, ResearchGate, Web of science, Scopus, etc).

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ORCID:https://orcid.org/0000-0002-5905-3727

SCOPUS: https://www.scopus.com/authid/detail.uri?origin=resultslist&authorId=55892683600&zone=

US National Library of Medicine (PubMed): https://pubmed.ncbi.nlm.nih.gov/?term=Aminu+N&cauthor_id=31493495

Google Scholar:https://scholar.google.com/citations?user=sWgtDLoAAAAJ&hl=en&oi=ao

ResearchGate:https://www.researchgate.net/profile/Nafiu_Aminu LinkedIn: https://www.linkedin.com/in/nafiu-aminu-576333148/