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Usmanu Danfodiyo University Sokoto

The Most Peaceful University in Nigeria








Prof. Suleiman Ahmed Isa



Area of specialization:Biomedical Science
Email:ahmed.suleiman@udusok.edu.ng,eldersuleiman@yahoo.com
Phone:+234(0)8039704944

List of Selected Publications

1. S.A Isa, LS Mainwaring, AW Thomas and R Webb (2009). The non-genomic effects of high doses of rosiglitazone on apoptosis and cell viability in cultured monocytic cells. Bayero Journal of Pure and Applied Sciences 2(2): 1-8
2. SA Isa, RHK Morris, AW Thomas and R Webb (2010). Oxidized LDL promotes apoptosis and expression of pro-inflammatory mediators in alternatively activated macrophages. Nigerian Journal of Basic and Applied Science 18(1): 50-57
3. Yakeu, G. Butcher, L. Isa, S. Webb, R. Roberts, A. Thomas, AW, Backx, K., James, PE., and Morris, K (2010). Low intensity exercise enhances expression of markers of alternative activation in circulating leukocytes: roles of PPARγ and Th2 cytokines Atherosclerosis 212(2)668-73
4. S.A. Isa, R.H.K. Morris, A.W. Thomas, R. Webb (2010). PPARγ Ligand Induced Unfolded Protein Responses in Monocytes and Macrophages. Nigerian Journal of Basic and Applied Science 18(2): 168-180
5. Caddy, J., Isa, S., Adam, E., Roberts, A., Lang, D., Morris, R.H.K., Thomas, A.W. and Webb, R (2010). Rosiglitazone Induces the Unfolded Protein Response, but Does Not Decrease Cell Viability, in Monocytic and Vascular Smooth Muscle Cells. Biochemical Biophysical Research Communications 400(4):689-695
6. Isa SA, Ruffino JS, Ahluwalia M, Thomas AW, Morris K, Webb R (2011). M2 macrophages exhibit higher sensitivity to oxLDL-induced lipotoxicity than other monocyte/macrophage subtypes. Lipids Health Dis. 2011 Dec 6;10:229
7. Thomas AW , Davies NA , Moir H , Watkeys L , Ruffino JS , Isa S.A , Butcher LR , Hughes MG , Morris K , Webb R (2012). Exercise-associated generation of PPARγ ligands activates PPARγ signaling events and upregulates genes related to lipid metabolism. J Appl Physiol. 112(5):806-15.
8. R.A Umar, S.W Hassan, A Lawal and S.A Isa (2013). Study on the conformation of insulin by solvent perturbation. International Journal of Biological and Chemical Science 7(1):427-432.
9. S.A Isa, K.G Ibrahim and I. Abubakar (2013). Effect of camel milk supplementation on serum glucose levels, lipid profile and body weight of alloxan-induced diabetic rats. Nigerian Journal of Basic and Applied Science 21(3):187-191
10. Dandare A, Isa S A, Ladan M J, Mainasara A S and Saidu Y. (2015). Serum Glucose and Lipid Profile in Salt-Induced Metabolic Syndrome Rats Treated with Camel Milk. International Journal of Scientific & Engineering Research, 6(9):734-740
11. Wali U., Saidu Y, Balarabe S. A, Suleiman A. I., Sahabi D. M, and Bilbis L. S: (2016) Lipid Peroxidation, Blood Pressure and lipid Profile of Diabetic Ischaemic Stroke Subjects. World Journal of Pharmacy and Pharmaceutical Sciences 5(4):296-301
12. A.S. Mainasara, S.A. Isa, A. Dandare, M.J. Ladan, Y. Saidu and S. Rabiu (2016): Blood pressure profile and insulin resistance in salt-induced hypertensive rats treated with camel milk. Mediterranean Journal of Nutrition and Metabolism 9(1):75–83
13. Ibrahim S.G., Umar R.A., Isa S.A. and Farouq A.A. (2016): Influence of preservation methods on pH and microbiological quality of tiger nut (Cyperus Esculentus) milk. Bayero Journal of Pure and Applied Sciences, 9(2): 234 – 242
14. Isa, A.S. Ibrahim, S.G., Umar, R.A., and Farouq, A.A (2016): Effect of Freezing and Heat Treatment on Proximate Composition and Bacteriological Quality of Tiger Nut (Cyperus esculentus) Milk. Proceedings of the 40 th Conference and Annual General meeting of the Nigerian Institute of Food Science and Technology, held at Coronation Hall, Government House, Kano. 24th to 26th October, 2016. Pp 428-430
15. Dandare, A., Isa, S. A., Ladan, M. J., Mainasara, A. S. And Saidu, Y (2016). Effect of Camel Milk Supplementation on Serum Oxidative Stress Markers in Salt-Induced Hypertensive Rats. Journal of Tropical Biosciences 11:143-151
16. Isa, S.A., Wali U., Balarabe, S.A, Yusuf, S. and Bilbis L.S. (2017). Renal and Hemaological Indices of Acute Ischaemic Stroke Subjects in Sokoto, Nigeria. World Journal of Pharmaceutical and Life Sciences 3(5):62-65
17. Suleiman A. Isa, Muazu G. Abubakar, Muhammed S. Abubakar, Muhammad A. Ubana, Abdullahi Dandare (2017). Effect of antioxidant rich nutraceuticals on histological changes due to high fat diet induced obesity in rats. American Journal of Research in Medical Sciences 1(1):8-13
18. Usman MJ, Saidu Y, Isa SA, Isezuo SA, Abbas AY, Dandare A and Bello A (2017): Lipid profile and haematological parameters of post-partum rats exposed to natron (kanwa). Nigerian Journal of Nutritional Sciences. 38(1)32-37.
19. Yusuf Saidu, Maimuna Jumai Usman, Suleiman Ahmed Isa, Simeon Alabi Isezuo, Lawal Suleiman Bilbis, Saddiku Malam Sahabi, Ahmed Bello and Suleiman alhaji Muhammad (2017): Biochemical and histological changes in the heart of post-partum rats exposed to natron. Indian Heart Journal. 70:887-893
20. Wali U., Saidu, Y., Isa S. A., Balarabe S. A., Abbas A. Y. and Bilbis L. S (2018). Effect of Antioxidant Vitamins and Minerals Supplementation on the Renal Functions and Haematological Indices of Acute Ischaemic Stroke Subjects in Sokoto, Nigeria. European Journal of Pharmaceutical and Medical Research 5(8):178-181
21. Suleiman Ahmed Isa, Kasimu Ghandi Ibrahim, Andrew Onu, Sagir Kaka Shinkafi, Rukayya Nuhu Ismail1, and Tijjani Salihu Shinkafi (2019). Hypolipidemic And Antioxidant Effects Of Camel Milk In High Fat Diet Fed Hyperlipidemic Rats. International Journal of Medical and Biomedical Studies. 3(2):143-153
22. Suleiman Ahmed Isa , Muhtari Ladan Jangebe , Aminu Bala Yabo and Halimatu Maiakwai Lamido (2020). Effect of Low Intensity Aerobic Exercise on Anthropometric Parameters and Cardiometabolic Risk Markers in Sedentary Individuals. Annals of Clinical and Experimental Medicine 1(2):97-101
23. Yusuf Saidu, Rihanat Olawumi Olaosebikan, Suleiman Ahmed Isa, Ibrahim Malami , Suleiman Alhaji Muhammad (2020). Effect of natron administration on the antioxidant status and lipid profile of rats. Journal of Food Science 85(11):4033-4038
24. Saidu Yusuf, Suleiman Ahmed Isa, Jibrin Baba, Turaki Abdullahi Aliyu and Yusuf Abdulrahman Bashir (2022). Functional properties and storage stability of optimized cereal-based complementary foods. Croatian Journal of Food Science and Technology 14 (1) 11
25. Saka, S.O.; Salisu, Y.Y.; Sahabi, H.M.; Sanusi, K.O.; Ibrahim, K.G.; Abubakar, M.B.; Isa, S.A.; Liman, M.G.; Shehu, S.; Malami, I.; et al. Nutrigenomic Effects of White Rice and Brown Rice on the Pathogenesis of Metabolic Disorders in a Fruit Fly Model. Molecules 2023, 28, 532. https://doi.org/10.3390/ molecules28020532
26. Kasimu Ghandi Ibrahim, Sagir Kaka Shinkafi, Aminu Ishaka and Suleiman Ahmed Isa (2023). Antidiabetic and Thrombolytic Activities of Some Selected Medicinal Plants in High Fat Diet and Dexamethasone-Induced Type 2 Diabetic Rats. Journal of African Association of Physiological Sciences 11(2);13-25
Presentations, Conferences, Seminars and Workshop
a) S. Isa, J. Caddy, L. Mainwaring, K. Morris, A. Thomas, R. Webb (2009). PPARgamma Ligand-induced Unfolded Protein Responses in Monocytes and Macrophages. Poster presented at the 9th Annual Postgraduate & Knowledge Transfer Partnership Colloquium, Gregynog United Kingdom 1-3 rd July 2009
b) S.A Isa. Thiazolidinediones for the treatment of type 2 diabetes. Paper presented at the 3 rd International Conference of Nigerian Students, Held at the University of Hull, Hull UK. 4 th - 5 th April, 2009.
c) Effective Researcher, A seminar organised by Research students skills development Unit, Cardiff University, Cardiff UK. 12 th –13 th May 2009.
d) SA Isa (2009). The Impact of Natural and Synthetic PPARγ Ligands on ER Stress and Unfolded Protein Responses. Oral presentation at the Cardiff School of Health Sciences Lunch time Research Seminar, University of Wales Institute Cardiff UK 28 th October, 2009.
e) Scientific Meeting of Calcium Signalling, organised by Ca 2+ Frontiers Cardiff. Held at Cardiff University Museum Avenue, Cardiff UK. 13 th May, 2010.
f) R Webb, S Isa, P James, K Morris, A Thomas (2011). Oxidised LDL-mediated disruption of ER membrane properties and differential sensitivity to lipotoxicity in diverse monocyte/macrophage sub-types: A novel mechanism to underpin the link between obesity and chronic inflammation? Poster presented at the Biochemical Society Annual Symposium - Recent Advances in Membrane Biochemistry, 5 - 7 Jan 2011
g) R. Webb, S.A. Isa, A.W. Thomas, K. Morris (2011). Enhanced sensitivity to oxidised LDL-mediated lipotoxicity in M2-polarised macrophages: A novel mechanism underpinning the link between obesity and obesity linked inflammatory diseases such as type-2 diabetes. Poster presented at the 4 th International Congress on Prediabetes and Metabolic Syndrome, Madrid Spain April 6-9, 2011
h) SA Isa (2012). Endoplasmic Reticulum Stress and Unfolded Protein Response: Role of PPARγ Gene and PPARγ Ligands. Oral Presentation at the Faculty of Science, Usmanu Danfodiyo University, Sokoto. 26 th April, 2012.
i) A 2-Day Intensive Workshop on Medical Education & Method of Assessment, organized by Usmanu Danfodiyo University Sokoto and Usmanu Danfodiyo University Teaching Hospital Sokoto. 21 st – 22 nd August, 2013.
j) Ibrahim, S.G., Umar, R.A., Isa, A.S. and Farouq, A.A (2016): Effect of Preservation Methods on the pH and Proximate Composition of Tiger Nut (Cyperus esculentus) Milk. Poster Presented at the 40 th Conference and Annual General meeting of the Nigerian Institute of Food Science and Technology, held at Coronation Hall, Government House, Kano. 24th to 26th October, 2016.
k) Tijjani Salihu Shinkafi, Musa Abbas, MAryam Bashir Dodo, Mohammed Hussaini Ruga, Muhammad Ramatu Dawa, Abubakar Aliyu, Suleiman Ahmed Isa and Ibrahim Hamza Kankia (2019). Antidiabetic Potential of Leaf Extracts of Cassia Sieberiana on Alloxan induced Diabetic rats. Paper presented at the 53 rd Annual Conference of Science Association of Nigeria (SAN). Held at Usmanu Danfodiyo University, Sokoto 14 th to 18 th July, 2019.
l) Yusuf, A.B., Saidu, Y., Isa, S.A., ad Jubrin, B (2019). Physico-chemical, Functional, and Sensorial attribute of Optimized complementary food formulations. Paper presented at the 53 rd Annual Conference of Science Association of Nigeria (SAN). Held at Usmanu Danfodiyo University, Sokoto 14 th to 18 th July, 2019.